Orthopedic filler

Durolane is indicated for intra-articular injection for the symptomatic treatment of mild to moderate osteoarthritis of the knee or hip. It is also indicated for the symptomatic treatment of mild to moderate osteoarthritis of other synovial joints and for pain relief following arthroscopic procedures. The product must be injected by a qualified physician in accordance with local legislation.

Durolane contains 20 mg/ml of stabilised non-animal hyaluronic acid (NASHA®) in a sodium chloride buffer solution at pH 7. It is a sterile, transparent viscoelastic gel supplied in a 3 ml glass syringe. The product is for single use only.

Hyaluronic acid is identical across all living organisms — a natural polysaccharide present in body tissues, with particularly high concentrations in synovial fluid and skin. Durolane is composed of biosynthetically produced, purified and stabilised hyaluronic acid, metabolised by the body via the same metabolic pathway as endogenous hyaluronic acid.

Contents
Each ml contains: Stabilised hyaluronic acid 20 mg, sodium chloride physiological solution pH 7 q.s.

Mechanism of action
Hyaluronic acid is a natural component of synovial fluid and acts within joints both as a lubricant for cartilage and ligaments and as a shock absorber. Intra-articular injections of hyaluronic acid restore viscosity and elasticity, reducing pain and improving joint mobility.

Medical device class III. For use only by healthcare professionals. Single use only. Read all package leaflet information before use.